The quest for peace, security, political and economic stability is pivotal not just to the United States, but to every state in the international system. In the aftermath of the September 11 attack, the Bush Administration increased efforts both home and abroad to prevent future attacks, build a more peaceful America and promote its national and economic interest abroad. The US national security strategies of 2002 and 2006 laid major emphasis in the importance of the African continent to US Security. Consequently, this gave rise to the sovereignty and stability of the African continent. It is said that the presence of AFRICOM threatens the national security, territorial integrity and political stability in Nigeria in the sense similar to the Middle East. The study examined the implications of AFRICOM in achieving effective peace and security in Nigeria and the consequences which it may have on Africa’s security and military development, especially in consideration of the fragility and volatility of the Nigerian state. The bulk of related data which were generated on the subject, as well as the adoption of the power theory, boosted our analytical strength and enhanced our prognosis. The research design employed was the descriptive research design, using the qualitative data analysis in analyzing the data gotten from the field and from research materials such as journals, articles, magazines, reports and internet materials. On the basis of this, the study unraveled that any U.S military intervention in Nigeria will inversely have both negative and positive impact on the Nigerian state and Africa in general. In view of this, it was recommended, that the Nigerian government should negotiate the redirection of the billions of US dollars, budgeted for AFRICOM’s operations, towards a clearly focused western styled multidimensional development initiative in Nigeria in order to guarantee peace and business friendly environment. More importantly, the institutions and the structures of the Nigerian Government should be revamped to meet the serious issue of development in the country, so that hunger, dissatisfaction and the inability to meet the citizens’ needs and expectations be met; as it is now, all these constitute serious security issues.